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Arab woman wearing a hijab with her hands on her face to represent mesotherapy

Mesotherapy explained – how it can treat skin and hair loss

Medically reviewed by
Dr. Sara Abdelrahim from The Branding Room

Developing wrinkles or having cellulite is a natural part of being human. However, if you would like to do something about them, mesotherapy might be for you.

Mesotherapy can help to smooth and nourish the texture of your skin, reducing the appearance of certain skin conditions and wrinkles by stimulating the production of collagen. It can even help to stimulate hair tissues and remove fat. But is it right for you?

Fast facts

  • Best results

    4 to 6 sessions

  • Duration of results

    12 to 18 months

  • Back to work

    Same day

  • Full recovery time

    A few days

  • Price range

    1,000 SAR to 2,000 SAR

  • Treatment duration

    30 to 60 minutes

  • Comfort

    OTC pain relief

  • Treatment type

    Minimally invasive

What is mesotherapy?

Mesotherapy treatment is a minimally invasive procedure that uses micro-injections to get vitamins and minerals, or any other specific drug or medication, into the skin. Although your body already produces these nutrients, they diminish with age, and mesotherapy tops them up in a bid to support and rejuvenate your overall complexion or correct certain issues.

Mesotherapy for skin

The treatment targets the middle layer, or mesoderm, of your skin to improve blood circulation, as well as collagen production. The injection grade ingredient or solution used depends on the area of focus, which will be discussed with an experienced practitioner beforehand. Solutions might include:

  • Hyaluronidase or collagenase enzymes.
  • Vitamins and minerals.
  • Herbal extracts.
  • Prescription medicines.

Mesotherapy for hair

You can also use mesotherapy for hair loss and alopecia. Much like the skin treatment, this involves injecting plant extracts, vitamins and medications – though this time directly into your hair’s follicles.

The treatment can help to stimulate the blood circulation of your scalp, promoting hair growth, and help to correct any hormone imbalances that may be preventing growth in and around the hair follicle.

Mesotherapy for fat loss

Phosphatidylcholine, a naturally occurring substance, can be injected into fatty tissues within the body – where it then acts to break down small, concentrated areas of excess fat. This is known as lipolysis. Other substances such as deoxycholate, deoxycholic acid or other compounds can be used in this procedure and are just as effective.

What can I expect during mesotherapy treatment?

Mesotherapy can be different for each person depending on their unique requirements and the solutions used to meet those needs. However, though the treatments differ, each follows a similar process when it comes to preparation and aftercare.

Before the treatment

Your practitioner will talk you through the information and guidance you need – including specific preparation advice. This will generally include taking a break from any products that might increase the sensitivity of your skin, such as strong exfoliants or actives.

You will also be told to avoid any blood thinning medication or herbal remedies for a few days before the treatment to decrease your chances of light bruising.

During the procedure

An average session can last between 30 minutes and one hour. A numbing cream might be applied to your skin to help you feel more comfortable. There are several different kinds of devices used for mesotherapy, including:

  • Ultra-fine short needles attached to syringes. Depending on your specific treatment, the needle will be inserted between one and four millimetres into the skin to better help penetrate the solution.
  • Electronic devices like a Mesogun or Dermapen.
  • Needle free mesotherapy when a combination of low current and ultrasound devices are used together and the targeted depth is adjusted according to your concern and skin type.


As mesotherapy is a relatively non-invasive treatment, you should feel quite comfortable after your appointment.

  • Take 24 hours after your treatment to relax, avoiding vigorous exercise.
  • Avoid direct sunlight for a few days, remembering SPF as you usually would.
  • Ask your chosen clinic which products to use or avoid as part of your aftercare.

Side-effects, prices and alternatives

How effective is mesotherapy?

Effectiveness often depends on your specific treatment and your body’s response to the solution. But research shows as many as 95 per cent of patients see improvements with fat reduction, for example.

How much does it cost?

The cost can vary depending on the clinic, but generally treatments will be priced between or SR1,000 and SR2,000.

Does mesotherapy hurt?

You may feel some mild discomfort, but any pain is usually minor and won’t require any medication to manage.

What are the side-effects?

Practitioners report minimal side-effects among patients. You may experience slight swelling and redness thanks to temporarily increased sensitivity, but this will usually fade within one to two days. There is also a low risk of bruising.

Is it safe?

Whether you are considering using mesotherapy for hair loss or skin health, the treatment is safe. Just remember to always go with an approved, qualified and experienced clinician.

What are the alternatives?

Your lifestyle and diet can have a big impact on your skin and overall health.

If you’re looking to give your skin a rejuvenating boost as part of a consistent routine, products like hyaluronic acid can help tighten the skin’s elasticity, while retinol can help smooth fine lines.

Keeping hydrated is also key – drinking three to four litres of water each day is highly recommended.

When it comes to alternative cosmetic treatments:

Mesotherapy facts

  • Mesotherapy was first researched and practised in 1952 by French doctor Michel Pistor in Paris.
  • It was initially used to treat migraines, respiratory treatments and varicose veins, and it wasn’t until the 1970s that practitioners discovered it could also improve skin texture.


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